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Are you looking to book up a cruise? Then look at our Mediterranean cruises departing from Rome. Thanks to this amazing trip, you can take in one of the most amazing cities in the world. At the same time, you can easily take in what was once a prime seat of governance for much of Europe. It’s for this reason that Rome is such a fine city to begin any cruise from.

You are not only guaranteed to have a tremendous time at sea; you are going to enjoy a much more satisfying experience overall. The end result? Absolute bliss!

We see many people booking up Mediterranean cruises departing from Rome today. The reason why is simple; they wish to take in much of the Mediterranean, but also experience one of its crown jewels. If you want to make sure that you have a tremendous time at sea whilst taking in the richness of Roman life, then book up for this kind of Mediterranean cruise.

You’ll be able to take in the richness of Rome and all that it offers. It also allows you the time that you need to really put in place the perfect starting point for transport.

Mediterranean Cruises Departing from Rome

One of the most challenging aspects of getting involved with any kind of Mediterranean cruise is setting up where to start. With Rome, you know that you are setting off on your journey from a rich and engrossing city. The kind of cultural capital that makes it easy for you to appreciate both past and present.

From the depth of the ancient architecture to the amazing venues that still stand from the Roman Empire, you’ll find yourself surrounded by a marvellous city. Add in the fact that you can experience everything from a trip to the Coliseum to the modern equivalent in the Stadio Olimpico, home to AS Roma and SS Lazio, two of the most prominent Italian football clubs.

Outside of culture and sport, Rome is a city with a rich nightlife and a tremendous cultural heart. From exploring old museums and seeing sights of what was once the hub of the most powerful empire on the planet, this gives you a way to enjoy a truly iconic capital of European culture.
From one capital, you then head to the next. Our Mediterranean cruises departing from Rome take in all manner of locations across the Mediterranean. This allows you to compare and contrast some of the richest and most stunning cities in the world, making it easy for you to put together a truly remarkable experience.
You can sail to all manner of different locations, too. Simply take a look at the options we have, and book up the Mediterranean cruise for you. Not only that, but this makes it very easy for you to make the right call and to start really moving forward with a dream vacation.
Don’t just settle for either Rome or the Mediterranean; combine both in a special cruise!

Italy, Spain & Marseille
 Sunday 26th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Luxury Large Ship Cruises
 Twin From $1,003 pp
 Quad From $1,421 pp
Italy, Greece & Turkey
 Sunday 26th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Odyssey Of The Seas
 Amazing Included Value
 Twin From $1,585 pp
 Quad From $1,214 pp
Mediterranean
 Monday 27th May 2024
Departing Rome (Civitavecchia)  
 14 Nights
 Queen Victoria
Cunard Sale  Cunard Sale
 Premium Cruise Line
 Twin From $2,172 pp
 Triple From $2,259 pp
Mediterranean
 Monday 27th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Queen Victoria
Cunard Sale  Cunard Sale
 Premium Cruise Line
 Twin From $1,179 pp
 Single From $2,063 pp
Italy, France & Spain
 Tuesday 28th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Luxury Large Ship Cruises
 Twin From $934 pp
 Quad From $987 pp
Spain, Cannes & Italy
 Wednesday 29th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Luxury Large Ship Cruises
 Twin From $1,046 pp
 Quad From $1,456 pp
Greece, Malta & Italy
 Wednesday 29th May 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Epic
 Twin From $2,565 pp
 Single From $4,954 pp
Italy, Spain & France
 Thursday 30th May 2024
Departing Rome (Civitavecchia)  
 9 Nights
 Norwegian Escape
Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
 Amazing Included Value
 Twin From $933 pp
 Quad From $1,132 pp
Greece, Izmir & Naples
 Friday 31st May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Luxury Large Ship Cruises
 Twin From $1,208 pp
 Quad From $3,172 pp
Italy, Spain & Marseille
 Sunday 2nd June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Luxury Large Ship Cruises
 Twin From $1,146 pp
 Quad From $1,316 pp
Italy, France & Spain
 Monday 3rd June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Musica
 Luxury Large Ship Cruises
 Twin From $1,084 pp
 Quad From $1,661 pp
Rome to Barcelona
 Tuesday 4th June 2024
Departing Rome (Civitavecchia)  
 9 Nights
 Celebrity Equinox
 Premium Cruise Line
 Twin From $1,124 pp
 Quad From $998 pp
Italy, France & Spain
 Tuesday 4th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Luxury Large Ship Cruises
 Twin From $860 pp
 Quad From $1,102 pp
Mediterranean
 Tuesday 4th June 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Viva
Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
 Amazing Included Value
 Twin From $1,499 pp
 Quad From $2,081 pp
Spain, Cannes & Italy
 Wednesday 5th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Luxury Large Ship Cruises
 Twin From $1,108 pp
 Quad From $1,173 pp
Greece, Izmir & Naples
 Friday 7th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Luxury Large Ship Cruises
 Twin From $1,158 pp
 Quad From $1,130 pp
Mediterranean
 Saturday 8th June 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Epic
 Twin From $1,349 pp
 Quad From $1,521 pp
Italy, Malta & Spain
 Saturday 8th June 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Escape
Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
 Amazing Included Value
 Twin From $1,434 pp
 Quad From $1,650 pp
Italy, Spain & Marseille
 Sunday 9th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Luxury Large Ship Cruises
 Twin From $3,393 pp
 Quad From $2,636 pp
Greece, Turkey & Italy
 Sunday 9th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Odyssey Of The Seas
 Amazing Included Value
 Twin From $1,905 pp
 Quad From $1,412 pp
Italy & Spain
 Monday 10th June 2024
Departing Rome (Civitavecchia)  
 14 Nights
 Queen Victoria
 Premium Cruise Line
 Twin From $2,172 pp
 Triple From $2,313 pp
Rome to Barcelona
 Monday 10th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Queen Victoria
White Star Service  White Star Service
 Premium Cruise Line
 Twin From $1,179 pp
 Triple From $1,102 pp
Italy, France & Spain
 Monday 10th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Musica
 Luxury Large Ship Cruises
 Twin From $1,189 pp
 Quad From $1,676 pp
Italy, France & Spain
 Tuesday 11th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Luxury Large Ship Cruises
 Twin From $841 pp
 Quad From $884 pp
Spain, Cannes & Italy
 Wednesday 12th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Luxury Large Ship Cruises
 Twin From $1,332 pp
 Quad From $1,354 pp
France, Italy & Spain
 Thursday 13th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Oasis Of The Seas
 Amazing Included Value
 Twin From $1,679 pp
 Quad From $1,308 pp
Greece, Izmir & Naples
 Friday 14th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Luxury Large Ship Cruises
 Twin From $1,084 pp
 Quad From $959 pp
Italy, Spain & Marseille
 Sunday 16th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Luxury Large Ship Cruises
 Twin From $1,270 pp
 Quad From $1,428 pp
Italy, France & Spain
 Monday 17th June 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Musica
 Luxury Large Ship Cruises
 Twin From $1,077 pp
 Quad From $1,782 pp
Rome to Barcelona
 Tuesday 18th June 2024
Departing Rome (Civitavecchia)  
 11 Nights
 Celebrity Ascent
 Premium Cruise Line
 Twin From $1,829 pp
 Quad From $1,209 pp